from ideal behaviour of the dynamics of the molecular tile self-assembly process. In this paper, we consider the effect on
the tile assembly process of a different kind of non-ideality, namely, imperfections in the tiles themselves. We assume a
scenario in which some small proportion of the tiles in a tile set are “malformed”. We study, through simulations, the effect
of such malformed tiles on the self-assembly process within the kinetic Tile Assembly Model (kTAM). Our simulation results
show that some tile set constructions show greater error-resilience in the presence of malformed tiles than others. For example,
the 2- and 3-way overlay compact proofreading tile sets of Reif et al. (DNA Computing 10, Lecture Notes in Computer Science,
vol 3384. Springer, 2005) are able to handle malformed tiles quite well. On the other hand, the snaked proofreading tile set of Chen and Goel (DNA
Computing 10, Lecture Notes in Computer Science, vol 3384. Springer, 2005) fails to form even moderately sized tile assemblies when malformed tiles are present. We show how the Chen–Goel construction
may be modified to yield new snaked proofreading tile sets that are resilient not only to errors intrinsic to the assembly
process, but also to errors caused by malformed tiles.
- Content Type Journal Article
- Pages 357-373
- DOI 10.1007/s11047-010-9234-9
- Authors
- Ya Meng, Department of Mathematics and Statistics, Queen’s University, Kingston, ON K7L 3N6, Canada
- Navin Kashyap, Department of Mathematics and Statistics, Queen’s University, Kingston, ON K7L 3N6, Canada
- Journal Natural Computing
- Online ISSN 1572-9796
- Print ISSN 1567-7818
- Journal Volume Volume 10
- Journal Issue Volume 10, Number 1